Squamous cell carcinoma of the breast.
Eur J Obstet Gynecol Reprod Biol
; 137(2): 222-6, 2008 Apr.
Article
en En
| MEDLINE
| ID: mdl-17481802
ABSTRACT
OBJECTIVE:
Pure squamous cell carcinoma (SCC) of the breast is a rare tumour and its clinical behaviour is not correctly known. The aim of the study is to evaluate the prevalence, epidemiological and clinical characteristics of the cases of SCC studied in our institution. STUDYDESIGN:
The breast department's database was searched for patients diagnosed with breast SCC between September 1979 and June 2006. Pathological features, outcome aspects and prognosis were studied. All specimens were reviewed by our pathologist who performed inmunohistochemistry for hormone receptors.RESULTS:
Eleven patients were identified (0.19%) between 5771 cases of breast cancer. Mean age was 64 (37-76) years and mean follow-up was 46 (6-216) months. Mean disease free survival (DFS) was 92 months (S.E.=33), with a 36% DFS rate at 5 years and the mean overall survival was 93 months (S.E.=34). Mean survival from the time recurrent disease was recognized was 9 (1-16) months. Tumours were hormone receptor negative.CONCLUSIONS:
SCC of the breast is aggressive and often treatment-refractory. The role of different new chemotherapy regimens need to be explored.
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Bases de datos:
MEDLINE
Asunto principal:
Neoplasias de la Mama
/
Carcinoma de Células Escamosas
Tipo de estudio:
Diagnostic_studies
/
Observational_studies
/
Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Adult
/
Aged
/
Female
/
Humans
/
Middle aged
Idioma:
En
Revista:
Eur J Obstet Gynecol Reprod Biol
Año:
2008
Tipo del documento:
Article