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Carcinoma of the tongue and bulbar-onset amyotrophic lateral sclerosis: unusual differential diagnosis.
Volanti, P; Mannino, M; Piccoli, T; La Bella, V.
Afiliación
  • Volanti P; ALS Clinical Research Center Department of Clinical Neurosciences, University of Palermo, Via G. La Loggia 1, I-90129, Palermo, Italy.
Neurol Sci ; 28(3): 151-3, 2007 Jun.
Article en En | MEDLINE | ID: mdl-17603768
We present a 72-year-old woman with progressive dysphagia, dysarthria and tongue palsy who was initially diagnosed with bulbar-onset amyotrophic lateral sclerosis (ALS). However, the absence of atrophy or fasciculations in the tongue, as in other voluntary muscles, and the lack of reproducible neurophysiological evidence of denervation, prompted a revision of the diagnostic work-up, which eventually led to the discovery of a carcinoma of the tongue. This case report describes a relatively rare type of oropharyngeal carcinoma that, in its early stage, resembled a bulbar-onset ALS. This differential diagnosis is unusual, and it was fostered by the persistent lack of atrophy of the tongue and the absence of spreading of signs and symptoms of motor neuron degeneration.
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Bases de datos: MEDLINE Asunto principal: Neoplasias de la Lengua / Carcinoma de Células Escamosas / Esclerosis Amiotrófica Lateral Tipo de estudio: Diagnostic_studies / Etiology_studies Límite: Aged / Female / Humans Idioma: En Revista: Neurol Sci Asunto de la revista: NEUROLOGIA Año: 2007 Tipo del documento: Article País de afiliación: Italia
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Bases de datos: MEDLINE Asunto principal: Neoplasias de la Lengua / Carcinoma de Células Escamosas / Esclerosis Amiotrófica Lateral Tipo de estudio: Diagnostic_studies / Etiology_studies Límite: Aged / Female / Humans Idioma: En Revista: Neurol Sci Asunto de la revista: NEUROLOGIA Año: 2007 Tipo del documento: Article País de afiliación: Italia