Unexpected degradation of the bisphosphonate P-C-P bridge under mild conditions.
Beilstein J Org Chem
; 4: 7, 2008 Jan 21.
Article
en En
| MEDLINE
| ID: mdl-18208588
ABSTRACT
Unexpected degradation of the P-C-P bridge from novel bisphosphonate derivative 1a and known etidronate trimethyl ester (1b) has been observed under mild reaction conditions. A proposed reaction mechanism for the unexpected degradation of 1a and 1b is also reported.
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Bases de datos:
MEDLINE
Idioma:
En
Revista:
Beilstein J Org Chem
Año:
2008
Tipo del documento:
Article
País de afiliación:
Finlandia