Lipophilic sugar nucleotide synthesis by structure-based design of nucleotidylyltransferase substrates.
Org Biomol Chem
; 6(3): 477-84, 2008 Feb 07.
Article
en En
| MEDLINE
| ID: mdl-18219417
ABSTRACT
Structure-based design of alkyl sugar-1-phosphates provides an efficient nucleotidylyltransferase-catalyzed synthesis of a series of new lipophilic sugar nucleotides possessing long or branched alkyl chains, thereby demonstrating the utility of nucleotidylyltransferases to catalyze the synthesis of sugar nucleotides with potential applications in lipopolysaccharide and lipoglycopeptide biosynthesis.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Pseudomonas aeruginosa
/
Nucleótidos
/
Nucleotidiltransferasas
Idioma:
En
Revista:
Org Biomol Chem
Asunto de la revista:
BIOQUIMICA
/
QUIMICA
Año:
2008
Tipo del documento:
Article