Two new coumarins from Herpetospermum caudigerum.
Chem Pharm Bull (Tokyo)
; 56(2): 192-3, 2008 Feb.
Article
en En
| MEDLINE
| ID: mdl-18239307
ABSTRACT
The ethyl acetate extract from the seeds of Herpetospermum caudigerum was found to show protective effects on carbon tetrachloride (CCl(4)) and thioacetamide (TAA)-induced acute hepatic injuries in mice. From the ethyl acetate extract, two new coumarins, herpetolide A (1) and herpetolide B (2), along with four known compounds, herpetone (3), dehydrodiconiferyl alcohol (4), 2,4-dihydroxypyrimidine (5) and stigmasterol (6) were isolated. The structures of the new coumarins were elucidated on the basis of chemical and physicochemical evidences. Herpetone exhibited protective effects on CCl(4)-induced hepatocyte injury.
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Bases de datos:
MEDLINE
Asunto principal:
Cucurbitaceae
/
Cumarinas
Límite:
Animals
Idioma:
En
Revista:
Chem Pharm Bull (Tokyo)
Año:
2008
Tipo del documento:
Article