Treatment of severe diabetic acidosis with tris-hydroxymethyl aminomethane in a thirteen-year-old child.
Minerva Anestesiol
; 74(3): 93-5, 2008 Mar.
Article
en En
| MEDLINE
| ID: mdl-18288072
ABSTRACT
Diabetic ketoacidosis is a severe complication of type I diabetes. A 13-year-old female (40 kg) patient was admitted to our Intensive Care Unit with severe metabolic acidosis (pH 6.8), hyperglycemia (835 mg/dL) and coma. Her hemodynamic conditions were unstable and, even though a large amount of plasma expanders, crystalloids, and inotropic support were supplied, the patient went into cardiac arrest in the first hour of treatment. After resuscitation, a better hemodynamic balance was achieved and metabolic acidosis was treated with fluid replacement therapy, continuous insulin infusion, and Tris-hydroxymethyl aminomethane (THAM) as a buffering agent. This therapy rapidly improved her metabolic conditions. The patient was discharged 5 days after Intensive Care Unit admission in good condition and without neurological sequelae.
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Bases de datos:
MEDLINE
Asunto principal:
Trometamina
/
Cetoacidosis Diabética
Límite:
Adolescent
/
Female
/
Humans
Idioma:
En
Revista:
Minerva Anestesiol
Año:
2008
Tipo del documento:
Article
País de afiliación:
Italia