Digital photography as an operational tool for assessing corticosteroid-induced lipodystrophy.
Eur J Intern Med
; 19(5): 340-4, 2008 Jul.
Article
en En
| MEDLINE
| ID: mdl-18549936
ABSTRACT
BACKGROUND:
Corticosteroid-induced lipodystrophy (CIL) is exclusively diagnosed in a subjective manner.OBJECTIVE:
To evaluate the reliability of digital photographs in the diagnosis of CIL.METHODS:
All consecutive patients starting long-term, high dosage corticosteroid therapy were photographed at baseline and after 3 months of therapy. At the end of the study, 3 physicians with expertise in corticosteroids classified patients as lipodystrophic yes/no/unclassifiable. Photographs analyses performed by 9 medical readers and evaluation of CIL using visual analog scale (VAS) performed during the M3 visit were compared to this classification.RESULTS:
Eighty-eight patients were monitored. Fifty of them were classified by the 3 experts as lipodystrophic and 30 as not lipodystrophic (8 were unclassifiable). Their intra- and inter-observer agreements were moderate or fair (kappa coefficientCONCLUSION:
The use of digital photographs do better than VAS to evaluate CIL. The accuracy of diagnosis improves with experience. Morphological changes are more important than morphological phenotype.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Prednisona
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Fotograbar
/
Glucocorticoides
/
Lipodistrofia
Tipo de estudio:
Evaluation_studies
Límite:
Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Eur J Intern Med
Asunto de la revista:
MEDICINA INTERNA
Año:
2008
Tipo del documento:
Article
País de afiliación:
Francia