Design and synthesis of a G-protein-coupled receptor antagonist library of aryloxyalkanolamines using a polymer-supported acyclic acetal linker.
J Comb Chem
; 11(1): 72-82, 2009.
Article
en En
| MEDLINE
| ID: mdl-19086798
ABSTRACT
A G-Protein-coupled receptor-targeted library of aryloxypropanolamines and aryloxybutanolamines was efficiently executed using a novel, polymer-supported acyclic acetal linker, producing compounds in good yields and purities.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Diseño de Fármacos
/
Receptores Acoplados a Proteínas G
/
Bibliotecas de Moléculas Pequeñas
/
Aminas
Límite:
Humans
Idioma:
En
Revista:
J Comb Chem
Asunto de la revista:
QUIMICA
Año:
2009
Tipo del documento:
Article
País de afiliación:
Estados Unidos