Altered gene expression in cloned piglets.
Reprod Fertil Dev
; 21(1): 60-6, 2009.
Article
en En
| MEDLINE
| ID: mdl-19152746
ABSTRACT
Studies on cloned pigs are scant compared with those in mice and cattle. Expression profiles of cloned pig embryos on full-term cloned pigs are even more limited owing to the limited availability of DNA microarray technology in the pig. We have conducted expression profile comparisons between pigs from somatic cell nuclear transfer and pigs from conventional breeding at birth and 1 month of age. Differentially expressed genes that are subjected to DNA methylation were also examined for their DNA methylation status. These data will be presented in the 2009 Annual Meeting of the International Embryo Transfer Society in San Diego. In the present review, we focus on summarising existing findings on epigenetic and other changes in cloned embryo, cloned pigs and their offspring by conventional breeding.
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Bases de datos:
MEDLINE
Asunto principal:
Regulación del Desarrollo de la Expresión Génica
/
Metilación de ADN
/
Clonación de Organismos
/
Sus scrofa
Límite:
Animals
Idioma:
En
Revista:
Reprod Fertil Dev
Asunto de la revista:
MEDICINA REPRODUTIVA
Año:
2009
Tipo del documento:
Article
País de afiliación:
Estados Unidos