High dose of red wine elicits enhanced inhibition of fibrinolysis.
Eur J Cardiovasc Prev Rehabil
; 16(2): 161-3, 2009 Apr.
Article
en En
| MEDLINE
| ID: mdl-19276983
ABSTRACT
BACKGROUND AND DESIGN:
The purpose of this randomized controlled cross-over study was to determine the acute effects of high doses of alcoholic beverages on circulating markers related to atherosclerosis and fibrinolysis.METHODS:
Twenty-two healthy men consumed a high dose (8.1+/-0.9 dl) of alcohol-containing red wine and dealcoholized red wine, and an equal ethanol dose of cognac (2.4+/-0.3 dl). Blood samples were taken before and shortly after interventions.RESULTS:
Red wine, unlike dealcoholized red wine and cognac, increased tissue plasminogen activator inhibitor-1 levels significantly, indicating an acute inhibition of fibrinolysis after a high dose.CONCLUSION:
Findings may explain the increased risk of cardiovascular mortality among binge drinkers.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Vino
/
Consumo de Bebidas Alcohólicas
/
Enfermedades Cardiovasculares
/
Etanol
/
Aterosclerosis
/
Fibrinólisis
Tipo de estudio:
Clinical_trials
Límite:
Adult
/
Humans
/
Male
Idioma:
En
Revista:
Eur J Cardiovasc Prev Rehabil
Asunto de la revista:
ANGIOLOGIA
/
CARDIOLOGIA
Año:
2009
Tipo del documento:
Article
País de afiliación:
Finlandia