Morphological changes of injected calcium phosphate cement in osteoporotic compressed vertebral bodies.
Osteoporos Int
; 20(12): 2063-70, 2009 Dec.
Article
en En
| MEDLINE
| ID: mdl-19300891
ABSTRACT
SUMMARY:
This study was undertaken to investigate the radiologic and clinical outcomes of vertebroplasty with calcium phosphate (CaP) cement in patients with osteoporotic vertebral compression fractures. The morphological changes of injected CaP cement in osteoporotic compressed vertebral bodies were variable and unpredictable. We suggest that the practice of vertebroplasty using CaP should be reconsidered.INTRODUCTION:
Recently, CaP, an osteoconductive filler material, has been used in the treatment of osteoporotic compression fractures. However, the clinical results of CaP-cement-augmented vertebrae are still not well established. The purpose of this study is to assess the clinical results of vertebroplasty with CaP by evaluating the morphological changes of CaP cement in compressed vertebral bodies.METHODS:
Fourteen patients have been followed for more than 2 years after vertebroplasty. The following parameters were reviewed age, sex, T score, compliance with osteoporosis medications, visual analog scale score, compression ratio, subsequent compression fractures, and any morphological changes in the filler material.RESULTS:
The morphological changes of injected CaP included reabsorption, condensation, bone formation (osteogenesis), fracture of the CaP solid hump, and heterotopic ossification. Out of 14 patients, 11 (78.6%) developed progression of the compression of the CaP-augmented vertebral bodies after vertebroplasty.CONCLUSIONS:
The morphological changes of the injected CaP cement in the vertebral bodies were variable and unpredictable. The compression of the CaP-augmented vertebrae progressed continuously for 2 years or more. The findings of this study suggest that vertebroplasty using CaP cement should be reconsidered.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Cementos para Huesos
/
Fosfatos de Calcio
/
Fracturas de la Columna Vertebral
/
Fracturas por Compresión
/
Fracturas Osteoporóticas
Tipo de estudio:
Diagnostic_studies
/
Evaluation_studies
/
Observational_studies
/
Prognostic_studies
Límite:
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Osteoporos Int
Asunto de la revista:
METABOLISMO
/
ORTOPEDIA
Año:
2009
Tipo del documento:
Article
País de afiliación:
Corea del Sur