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Occlusive therapy in atopic dermatitis: overview.
Braham, Sabrina J; Pugashetti, Rupa; Koo, John; Maibach, Howard I.
Afiliación
  • Braham SJ; Department of Pediatrics, Lucile Packard Children's Hospital at Stanford, Palo Alto, California, USA.
J Dermatolog Treat ; 21(2): 62-72, 2010 Mar.
Article en En | MEDLINE | ID: mdl-19444691
INTRODUCTION: Occlusive therapy, including both dry and wet ('wet-wrap therapy') offers a treatment option in atopic dermatitis (AD) which may be underutilized in clinical practice due to concerns about burdensome regimens and potential complications. This review examines current evidence for the use of occlusion in AD. METHODS: Keyword and title searches in PubMed and EMBASE were used to examine data on the use of occlusive therapy in AD from January 1966 to February 2009. RESULTS: Eighteen studies were found examining the use of occlusive therapy in AD. Of the 14 studies examining wet-wrap therapy, five were randomized controlled trials. All wet-wrap therapy studies demonstrated efficacy in severe or acute, moderate and chronic AD. Of the four studies examining dry occlusive therapy, a single controlled study of dry occlusion does not support a benefit over conventional open therapy. Increased cutaneous bacterial counts or clinical infection were reported in all studies using dry occlusion and in four of 14 studies utilizing wet-wrapping techniques. CONCLUSIONS: Available data are encouraging, though limited by the lack of adequate study controls and standardized designs. More controlled trials are indicated.
Asunto(s)

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Dermatitis Atópica / Apósitos Oclusivos Tipo de estudio: Clinical_trials / Systematic_reviews Límite: Humans Idioma: En Revista: J Dermatolog Treat Asunto de la revista: DERMATOLOGIA Año: 2010 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Dermatitis Atópica / Apósitos Oclusivos Tipo de estudio: Clinical_trials / Systematic_reviews Límite: Humans Idioma: En Revista: J Dermatolog Treat Asunto de la revista: DERMATOLOGIA Año: 2010 Tipo del documento: Article País de afiliación: Estados Unidos