Accelerated spectroscopic imaging of hyperpolarized C-13 pyruvate using SENSE parallel imaging.
NMR Biomed
; 22(8): 867-73, 2009 Oct.
Article
en En
| MEDLINE
| ID: mdl-19489035
ABSTRACT
The ability to accelerate the spatial encoding process during a chemical shift imaging (CSI) scan of hyperpolarized compounds is demonstrated through parallel imaging. A hardware setup designed to simultaneously acquire (13)C data from multiple receivers is presented here. A system consisting of four preamplifiers, four gain stages, a transmit coil, and a four receive channel rat coil was built for single channel excitation and simultaneous multi-channel detection of (13)C signals. The hardware setup was integrated with commercial scanner electronics, allowing the system to function similar to a conventional proton multi-channel setup, except at a different frequency. The ability to perform parallel imaging is demonstrated in vivo. CSI data from the accelerated scans are reconstructed using a self-calibrated multi-spectral parallel imaging algorithm, by using lower resolution coil sensitivity maps obtained from the central region of k-space. The advantages and disadvantages of parallel imaging in the context of imaging hyperpolarized compounds are discussed.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Radioisótopos de Carbono
/
Imagen por Resonancia Magnética
/
Aumento de la Imagen
/
Ácido Pirúvico
Tipo de estudio:
Evaluation_studies
Límite:
Animals
/
Humans
Idioma:
En
Revista:
NMR Biomed
Asunto de la revista:
DIAGNOSTICO POR IMAGEM
/
MEDICINA NUCLEAR
Año:
2009
Tipo del documento:
Article
País de afiliación:
Estados Unidos