Nodular malignant melanoma and multiple cutaneous neoplasms under immunosuppression with azathioprine.
Melanoma Res
; 19(4): 271-3, 2009 Aug.
Article
en En
| MEDLINE
| ID: mdl-19550360
ABSTRACT
Immunosuppressed patients are at increased risk of skin cancer. A 67-year-old renal transplant recipient developed a nodular malignant melanoma after 30 years of immunosuppression with azathioprine and prednisolone. The patient died of metastatic disease 3 months after the diagnosis was made. The function of the renal graft was not affected at all. Renal transplant recipients are at high risk of developing nonmelanocytic skin tumors when on immunosuppressive therapy with cyclosporine A. Less common is the development of skin cancer during immunosuppression with azathioprine. Latest reports show the increased incidence of malignant melanoma in immunosuppressed patients. Our case illustrates the necessity of close dermatological surveillance of allograft recipients, to assure an early recognition of any malignant skin tumor and to reduce the risk of systemic metastatic disease.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Neoplasias Cutáneas
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Azatioprina
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Trasplante de Riñón
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Inmunosupresores
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Melanoma
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Neoplasias Primarias Múltiples
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
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Screening_studies
Límite:
Aged
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Humans
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Male
Idioma:
En
Revista:
Melanoma Res
Asunto de la revista:
NEOPLASIAS
Año:
2009
Tipo del documento:
Article
País de afiliación:
Alemania