Familial small cell carcinoma of the ovary.
Pediatr Blood Cancer
; 53(7): 1334-6, 2009 Dec 15.
Article
en En
| MEDLINE
| ID: mdl-19621450
ABSTRACT
Ovarian tumors have a low incidence in childhood, accounting for 1% of malignancies within the ages of 0-17 years. Small cell carcinoma of the ovary is a rare histology and historically has a poor prognosis. We report a case of an 11-year-old female diagnosed with small cell carcinoma of the ovary and hypercalcemia (SCCOHT). There was a strong family history of the disease, a reduction in the age of onset in the proband, and the absence of BRCA mutations. This case suggests the phenomenon of genetic anticipation in an ovarian cancer.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Neoplasias Ováricas
/
Carcinoma de Células Pequeñas
/
Anticipación Genética
Tipo de estudio:
Etiology_studies
/
Incidence_studies
/
Prognostic_studies
Idioma:
En
Revista:
Pediatr Blood Cancer
Asunto de la revista:
HEMATOLOGIA
/
NEOPLASIAS
/
PEDIATRIA
Año:
2009
Tipo del documento:
Article
País de afiliación:
Estados Unidos