[Biochemical markers of bone turnover. New aspect. Bone metabolic markers available in daily practice].
Clin Calcium
; 19(8): 1075-82, 2009 Aug.
Article
en Ja
| MEDLINE
| ID: mdl-19638690
ABSTRACT
Changes of bone remodeling markers reflect bone growth and bone turnover. Information on bone metabolism can be attained by blood and urine laboratory tests. Recently developed bone specific markers are categorized by bone remodeling process, i.e. bone formation and resorption. The formation markers include bone-specific alkaline phosphatase (BAP), osteocalcin (OC), undercarboxylated osteocalcin (ucOC), procollagene type I C- and N-terminal peptides (P1CP and P1NP). Bone resorption markers include deoxypyridinoline, collagen I C- and N-terminal telopeptides (CTX and NTX) , and tartrate resistent acid phosphatase (TRACP) isoform 5b. These laboratory tests offer lots of advantages for the diagnosis of bone metabolic disorders and for the evaluation of clinical states of primary osteoporosis and other metabolic skeletal diseases.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Osteogénesis
/
Huesos
/
Desarrollo Óseo
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Enfermedades Óseas Metabólicas
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Biomarcadores
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Remodelación Ósea
Tipo de estudio:
Diagnostic_studies
Límite:
Humans
Idioma:
Ja
Revista:
Clin Calcium
Asunto de la revista:
METABOLISMO
Año:
2009
Tipo del documento:
Article