Quantitative megavoltage radiation therapy dosimetry using the storage phosphor KCl: Eu2+.
Med Phys
; 36(8): 3748-57, 2009 Aug.
Article
en En
| MEDLINE
| ID: mdl-19746808
ABSTRACT
This work, for the first time, reports the use of europium doped potassium chloride (KClEu2+) storage phosphor for quantitative megavoltage radiation therapy dosimetry. In principle, KClEu2+ functions using the same photostimulatated luminescence (PSL) mechanism as commercially available BaFBr0.85I0.15Eu2+ material that is used for computed radiography (CR) but features a significantly smaller effective atomic number--18 versus 49--making it a potentially useful material for nearly tissue-equivalent radiation dosimetry. Cylindrical KClEu2+ dosimeters, 7 mm in diameter and 1 mm thick, were fabricated in-house. Dosimetric properties, including radiation hardness, response linearity, signal fading, dose rate sensitivity, and energy dependence, were studied with a laboratory optical reader after irradiation by a linear accelerator. The overall experimental uncertainty was estimated to be within +/-2.5%. The findings were (1) KClEu2+ showed satisfactory radiation hardness. There was no significant change in the stimulation spectra after irradiation up to 200 Gy when compared to a fresh dosimeter, indicating that this material could be reused at least 100 times if 2 Gy per use was assumed, e.g., for patient-specific IMRT QA. (2) KClEu2+ exhibited supralinear response to dose after irradiation from 0 to 800 cGy. (3) After x ray irradiation, the PSL signal faded with time and eventually reached a fading rate of about 0.1 % /h after 12 h. (4) The sensitivity of the dosimeter was independent of the dose rate ranging from 15 to 1000 cGy/min. (5) The sensitivity showed no beam energy dependence for either open x ray or megavoltage electron fields. (6) Over-response to low-energy scattered photons was comparable to radiographic film, e.g., Kodak EDR2 film. By sandwiching dosimeters between low-energy photon filters (0.3 mm thick lead foils) during irradiation, the over-response was reduced. The authors have demonstrated that KClEu2+ dosimeters have many desirable dosimetric characteristics that make the material conducive to radiation therapy dosimetry. In the future, a large-area KClEu2+-based CR plate with a thickness of the order of a few microns, created using modern thin film techniques, could provide a reusable, quantitative, high-resolution two-dimensional dosimeter with minimal energy dependence.
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Bases de datos:
MEDLINE
Asunto principal:
Cloruro de Potasio
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Radiometría
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Sustancias Luminiscentes
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Europio
Idioma:
En
Revista:
Med Phys
Año:
2009
Tipo del documento:
Article
País de afiliación:
Estados Unidos