Differentiation between true focal liver lesions and pseudolesions in patients with fatty liver: evaluation of helical CT criteria.
Eur Radiol
; 20(7): 1726-37, 2010 Jul.
Article
en En
| MEDLINE
| ID: mdl-20084385
ABSTRACT
OBJECTIVE:
To determine the potential of helical CT for differentiating true lesions from pseudolesions in patients with fatty liver.METHODS:
Helical CT of 44 patients with diffuse fatty liver (22 with true lesions; 22 with pseudolesions) were reviewed by two observers with regard to morphological features of visible lesions. Univariate analysis was used to detect discriminating criteria for the diagnosis of true lesions.RESULTS:
Interobserver agreement was excellent for 9/10 morphological criteria (kappa = 0.831-1). True lesions were more frequently distant from the liver capsule (50.00% vs. 4.55%), located in the right lobe (72.73% vs. 31.82%), round (86.36% vs. 54.55%), heterogeneous (27.27% vs. 0.00%) and had ill-defined margins (40.91% vs. 13.64%) compared with pseudolesions (P < 0.05). Using univariate analysis, a location distant from the liver capsule was the most discriminating variable to differentiate between true and pseudolesions (P = 0.0060). Hyperattenuating content and round shape were the most sensitive criteria (sensitivity = 90.91% and 86.36%, respectively) for the diagnosis of true lesions, and heterogeneity, vascular displacement and encapsulation were the three most specific ones (specificity = 100.00%). Best accuracy was obtained with an association of the three variables (accuracy = 86.36%).CONCLUSION:
Helical CT provides objective and discriminating morphological criteria to differentiate between true lesions and pseudolesions in patients with fatty liver.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Tomografía Computarizada Espiral
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Hígado Graso
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Neoplasias Hepáticas
Tipo de estudio:
Diagnostic_studies
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Evaluation_studies
Límite:
Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Eur Radiol
Asunto de la revista:
RADIOLOGIA
Año:
2010
Tipo del documento:
Article
País de afiliación:
Francia