Lung cancer: Morphological and functional approach to screening, staging and treatment planning.
Future Oncol
; 6(3): 367-80, 2010 Mar.
Article
en En
| MEDLINE
| ID: mdl-20222794
ABSTRACT
Lung cancer is a major problem in public health and constitutes the leading cause of cancer-related mortality in the world. Lung cancer screening with low-dose computed tomography is promising but needs to overcome many difficulties, such as the large number of incidentally discovered nodules, the radiation dose delivered to the patient during a whole screening program and its cost. The ultimate target point represented by the reduction of lung cancer-related mortality needs to be proved in large, well-designed, randomized, multicenter, prospective trials. Lung cancer staging by morphological tools seems to be limited owing to the presence of metastases in normal-sized lymph nodes. In this context, multidetector computed tomography cannot be used alone but is useful in conjunction with molecular imaging and MRI. Today, flurodeoxglucose PET-CT appears to be the most accurate method for lung cancer staging and may prevent unnecessary thoracotomies. For treatment planning, flurodeoxglucose PET-CT is playing an increasing role in radiotherapy planning at the target selection and definition steps.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Diagnóstico por Imagen
/
Tamizaje Masivo
/
Neoplasias Pulmonares
Tipo de estudio:
Clinical_trials
/
Diagnostic_studies
/
Prognostic_studies
/
Screening_studies
Límite:
Adult
/
Aged
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Future Oncol
Año:
2010
Tipo del documento:
Article
País de afiliación:
Bélgica