Cardiotoxicity with 5-fluorouracil and capecitabine: more than just vasospastic angina.
Intern Med J
; 40(4): 303-7, 2010 Apr.
Article
en En
| MEDLINE
| ID: mdl-20529041
ABSTRACT
In this case series we present a variety of different cardiac toxicities with 5-fluorouracil and its pro-drug capecitabine, including myocardial infarction, cardiomyopathy, sinoatrial and atrioventricular node dysfunction, takotsubo cardiomyopathy and QT prolongation with torsade-de pointes ventricular tachycardia. We stress the fact that while vasospasm is a well-recognized side-effect of this class of chemotherapeutic agent, broader cardiotoxicity is commonly seen and an increased awareness of the range of toxicity is necessary if repeat toxicity is to be avoided.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Vasoespasmo Coronario
/
Desoxicitidina
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Cardiotoxinas
/
Fluorouracilo
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Angina Inestable
Tipo de estudio:
Diagnostic_studies
Límite:
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Intern Med J
Asunto de la revista:
MEDICINA INTERNA
Año:
2010
Tipo del documento:
Article
País de afiliación:
Australia