Intracellular imaging of HeLa cells by non-functionalized NaYF4 : Er3+, Yb3+ upconverting nanoparticles.
Nanoscale
; 2(4): 495-8, 2010 Apr.
Article
en En
| MEDLINE
| ID: mdl-20644749
ABSTRACT
We report on the efficient incorporation of non-functionalized NaYF(4) Er(3+), Yb(3+) nanoparticles inside HeLa live cancer cells by direct endocytosis. The efficient two-photon excited near-infrared-to-visible upconversion fluorescence of these nanoparticles is then used to obtain high-contrast intracellular fluorescence images of single cells. These images reveal a redistribution of the nanoparticles inside the cell as the incubation time increases. Thus, non-functionalized NaYF(4) Er(3+), Yb(3+) nanoparticles emerge as very promising fluorescence probes for real-time imaging of cellular dynamics.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Iterbio
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Itrio
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Erbio
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Nanopartículas
Límite:
Humans
Idioma:
En
Revista:
Nanoscale
Año:
2010
Tipo del documento:
Article
País de afiliación:
Canadá