A randomized trial of viral hepatitis prevention among underprivileged people in the Lyon area of France.
J Public Health (Oxf)
; 33(2): 182-92, 2011 Jun.
Article
en En
| MEDLINE
| ID: mdl-20876189
ABSTRACT
BACKGROUND:
We compared the efficacy of two viral hepatitis B and C (VHBC) screening strategies, relative to no intervention, among underprivileged people (UP) living in shelters in the Lyon area.METHODS:
Eighteen of 37 shelters were randomly sampled after stratification based on the accommodation capacity and the screening centres/shelters distance. Through randomization, the S0 strategy (no intervention), the S1 strategy [group information (GI) and referral for screening] and the S2 strategy (GI and in situ screening) were each applied in six shelters. A standardized questionnaire was offered to each participant. Follow-up of positive cases was organized via the reference centre of VHBC of Lyon.RESULTS:
The screening completion rate (SCR) among 1276 included subjects in S0, S1 and S2 was 1.5, 42.8 and 59.7%, respectively (P < 10(-6)). This rate was higher in S2 regardless of the sociodemographic variable considered. Odds ratios (OR) of screening completion (SC) was significantly higher in S1 versus S0, OR = 49.8 [95% confidence interval (CI) 26.1-102.1], in S2 versus S0, OR = 98.5 (95% CI 51.9-200.8) and in S2 versus S1, OR = 2.0 (95% CI 1.3-2.9). Age, country of birth and professional inactivity were independently associated with SC.CONCLUSIONS:
Health authorities must ensure widespread screening of UP, which is more effective when conducted in shelters than in screening centres.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Hepatitis C
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Hepatitis B
Tipo de estudio:
Clinical_trials
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Etiology_studies
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Prognostic_studies
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Risk_factors_studies
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Screening_studies
Límite:
Adolescent
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Adult
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Female
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Humans
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Male
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Middle aged
País/Región como asunto:
Europa
Idioma:
En
Revista:
J Public Health (Oxf)
Año:
2011
Tipo del documento:
Article
País de afiliación:
Francia