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Metalloproteins and the pyrite-based origin of life: a critical assessment.
Rivas, Mario; Becerra, Arturo; Peretó, Juli; Bada, Jeffrey L; Lazcano, Antonio.
Afiliación
  • Rivas M; Facultad de Ciencias, Universidad Nacional Autónoma de México, México DF, Mexico.
Orig Life Evol Biosph ; 41(4): 347-56, 2011 Aug.
Article en En | MEDLINE | ID: mdl-21431891
We critically examine the proposal by Wächtershäuser (Prokaryotes 1:275-283, 2006a, Philos Trans R Soc Lond B Biol Sci 361: 787-1808, 2006b) that putative transition metal binding sites in protein components of the translation machinery of hyperthermophiles provide evidence of a direct relationship with the FeS clusters of pyrite and thus indicate an autotrophic origin of life in volcanic environments. Analysis of completely sequenced cellular genomes of Bacteria, Archaea and Eucarya does not support the suggestion by Wächtershäuser (Prokaryotes 1:275-283, 2006a, Philos Trans R Soc Lond B Biol Sci 361: 787-1808, 2006b) that aminoacyl-tRNA synthetases and ribosomal proteins bear sequence signatures typical of strong covalent metal bonding whose absence in mesophilic species reveals a process of adaptation towards less extreme environments.
Asunto(s)

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Sulfuros / Coenzimas / Origen de la Vida / Aminoacil-ARNt Sintetasas / Hierro / Metaloproteínas Idioma: En Revista: Orig Life Evol Biosph Asunto de la revista: BIOLOGIA / BIOLOGIA MOLECULAR Año: 2011 Tipo del documento: Article País de afiliación: México

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Sulfuros / Coenzimas / Origen de la Vida / Aminoacil-ARNt Sintetasas / Hierro / Metaloproteínas Idioma: En Revista: Orig Life Evol Biosph Asunto de la revista: BIOLOGIA / BIOLOGIA MOLECULAR Año: 2011 Tipo del documento: Article País de afiliación: México