[Distribution of apoE phenotypes and frequencies of apoE alleles in Mongolian population].
Zhongguo Yi Xue Ke Xue Yuan Xue Bao
; 12(3): 223-6, 1990 Jun.
Article
en Zh
| MEDLINE
| ID: mdl-2150360
ABSTRACT
Distribution of apoE3/3, E3/4 and E2/3 were 88.2%, 9.7% and 2.2%, respectively, in a Mongolian population. No apoE2/2, E2/4 or E4/4 phenotypes were found in this study. The population of apo E3/3 and frequency of epsilon 3 in this Mongolian population were significantly higher than those of Western populations and the Han nationality of China. The above results indicated that apoE phenotypes are closely related to lipid levels. The cholesterol levels of individuals with apoE3/3 phenotype were much lower than those of individuals with apoE2/3 (P less than 0.01) and higher than those of individuals with apoE3/4 (P less than 0.05). The levels of apoA-1 of individuals with apoE3/3 were much lower than those of individuals with apoE2/3 (P less than 0.01), but no difference was found between apoE3/3 and apoE3/4 phenotypes (P greater than 0.05).
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Bases de datos:
MEDLINE
Asunto principal:
Apolipoproteínas E
/
Alelos
Límite:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
País/Región como asunto:
Asia
Idioma:
Zh
Revista:
Zhongguo Yi Xue Ke Xue Yuan Xue Bao
Año:
1990
Tipo del documento:
Article