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Multisource modeling of flattening filter free (FFF) beam and the optimization of model parameters.
Cho, Woong; Kielar, Kayla N; Mok, Ed; Xing, Lei; Park, Jeong-Hoon; Jung, Won-Gyun; Suh, Tae-Suk.
Afiliación
  • Cho W; Department of Biomedical Engineering and Research Institute of Biomedical Engineering, College of Medicine, The Catholic University of Korea, Seoul 137-701, Korea.
Med Phys ; 38(4): 1931-42, 2011 Apr.
Article en En | MEDLINE | ID: mdl-21626926
ABSTRACT

PURPOSE:

With the introduction of flattening filter free (FFF) linear accelerators to radiation oncology, new analytical source models for a FFF beam applicable to current treatment planning systems is needed. In this work, a multisource model for the FFF beam and the optimization of involved model parameters were designed.

METHODS:

The model is based on a previous three source model proposed by Yang et al. ["A three-source model for the calculation of head scatter factors," Med. Phys. 29, 2024-2033 (2002)]. An off axis ratio (OAR) of photon fluence was introduced to the primary source term to generate cone shaped profiles. The parameters of the source model were determined from measured head scatter factors using a line search optimization technique. The OAR of the photon fluence was determined from a measured dose profile of a 40 x 40 cm2 field size with the same optimization technique, but a new method to acquire gradient terms for OARs was developed to enhance the speed of the optimization process. The improved model was validated with measured dose profiles from 3 x 3 to 40 x 40 cm2 field sizes at 6 and 10 MV from a TrueBeam STx linear accelerator. Furthermore, planar dose distributions for clinically used radiation fields were also calculated and compared to measurements using a 2D array detector using the gamma index method.

RESULTS:

All dose values for the calculated profiles agreed with the measured dose profiles within 0.5% at 6 and 10 MV beams, except for some low dose regions for larger field sizes. A slight overestimation was seen in the lower penumbra region near the field edge for the large field sizes by 1%-4%. The planar dose calculations showed comparable passing rates (> 98%) when the criterion of the gamma index method was selected to be 3%/3 mm.

CONCLUSIONS:

The developed source model showed good agreements between measured and calculated dose distributions. The model is easily applicable to any other linear accelerator using FFF beams as the required data include only the measured PDD, dose profiles, and output factors for various field sizes, which are easily acquired during conventional beam commissioning process.
Asunto(s)

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Planificación de la Radioterapia Asistida por Computador / Modelos Teóricos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Med Phys Año: 2011 Tipo del documento: Article

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Planificación de la Radioterapia Asistida por Computador / Modelos Teóricos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Med Phys Año: 2011 Tipo del documento: Article