Highly chromic, proton-responsive phenyl pyrimidones.
Org Lett
; 13(16): 4188-91, 2011 Aug 19.
Article
en En
| MEDLINE
| ID: mdl-21790121
Aryl pyrimidones are pharmacologically relevant compounds whose optical properties have only been partially explored. We report the synthesis and optical characterization of a series of aryl- and diaryl-2(1H)-pyrimidones. The electronic transitions of these chromophores are modulated by the extent of conjugation between the pendant phenyl ring and the pyrimidone core as well as the presence of electron-donating auxochromes. Monoprotonation of the pyrimidone ring results in large hyperchromic and bathochromic shifts as well as switching of fluorescence making these phenyl pyrimidones of interest as sensory materials.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Protones
/
Pirimidinonas
Idioma:
En
Revista:
Org Lett
Asunto de la revista:
BIOQUIMICA
Año:
2011
Tipo del documento:
Article
País de afiliación:
Estados Unidos