Combining two-directional synthesis and tandem reactions: a short formal synthesis of halichlorine.

Gignoux, Camille; Newton, Annabella F; Barthelme, Alexandre; Lewis, William; Alcaraz, Marie-Lyne; Stockman, Robert A

Gignoux, Camille; Newton, Annabella F; Barthelme, Alexandre; Lewis, William; Alcaraz, Marie-Lyne; Stockman, Robert A.

Afiliación

Gignoux C; School of Chemistry, University of Nottingham, Nottingham, UK NG7 2RD.

Org Biomol Chem ; 10(1): 67-9, 2012 Jan 07.

Article en En | MEDLINE | ID: mdl-22027866

ABSTRACT

ABSTRACT

A short and efficient synthesis of an advanced intermediate (1) in the Clive route to halichlorine has been achieved in 12 steps and 13.2% yield by a combined two-directional synthesis/tandem reaction strategy.

Asunto(s)

Alcaloides/síntesis química; Compuestos de Espiro/síntesis química

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Compuestos de Espiro / Alcaloides Idioma: En Revista: Org Biomol Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2012 Tipo del documento: Article

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