[Optimization of ultrasonic-assisted extraction of total flavonoids from leaves of the Artocarpus heterophyllus by response surface methodology].
Zhong Yao Cai
; 34(7): 1125-9, 2011 Jul.
Article
en Zh
| MEDLINE
| ID: mdl-22066410
ABSTRACT
OBJECTIVE:
To investigate the ultrasonic-assisted extract on of total flavonoids from leaves of the Artocarpus heterophyllus.METHODS:
Investigated the effects of ethanol concentration, extraction time, and liquid-solid ratio on flavonoids yield. A 17-run response surface design involving three factors at three levels was generated by the Design-Expert software and experimental data obtained were subjected to quadratic regression analysis to create a mathematical model describing flavonoids extraction.RESULTS:
The optimum ultrasonic assisted extraction conditions were ethanol volume fraction 69.4% and liquid-solid ratio of 22.61 for 32 min. Under these optimized conditions, the yield of flavonoids was 7.55 mg/g.CONCLUSION:
The Box-Behnken design and response surface analysis can well optimize the ultrasonic-assisted extraction of total flavonoids from Artocarpus heterophyllus.
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Bases de datos:
MEDLINE
Asunto principal:
Ultrasonido
/
Flavonoides
/
Tecnología Farmacéutica
/
Artocarpus
Tipo de estudio:
Prognostic_studies
Idioma:
Zh
Revista:
Zhong Yao Cai
Asunto de la revista:
TERAPIAS COMPLEMENTARES
Año:
2011
Tipo del documento:
Article
País de afiliación:
China