Serial brain MRI in TIA patients.
J Neuroradiol
; 39(3): 137-41, 2012 Jul.
Article
en En
| MEDLINE
| ID: mdl-22742940
ABSTRACT
OBJECTIVE:
Up to 40% of patients with transient ischemic attack (TIA) demonstrate lesions on diffusion-weighted magnetic resonance imaging (DWI). However, the time course of these ischemic lesions is not well known. Some lesions could vanish soon after symptom onset whereas others could be visible only after a certain delay. Based on a population of TIA patients imaged twice with DWI within the first week after onset, our aim was to estimate the rate of patients with DWI reversible ischemic lesion or with delayed DWI positivity.METHODS:
We retrospectively compared DWI at admission (DWI(1), median = 15 hours after TIA) with follow-up DWI (DWI(2), median = 47 hours) in 64 consecutive TIA over a 7-month period. DWI was reviewed in consensus by two readers, blinded to clinical information. Number, extent and arterial distribution of lesions were assessed.RESULTS:
DWI(1) and DWI(2) showed similar findings in 55 TIA patients (32 with and 23 without ischemic lesions). In nine (14%) patients, changes were observed on DWI(2) presence of ischemic lesions despite normal DWI(1) (n = 3), increase in lesion size (n = 3), or partial or complete lesion reversibility (n = 3).CONCLUSION:
In most TIA cases, ischemic lesions captured by early DWI and 48-hour DWI are similar. However, some ischemic lesions vanish rapidly while lesion visibility is delayed in other cases.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Encéfalo
/
Ataque Isquémico Transitorio
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Técnica de Sustracción
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Imagen de Difusión por Resonancia Magnética
Tipo de estudio:
Diagnostic_studies
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Observational_studies
Límite:
Aged
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Female
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Humans
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Male
Idioma:
En
Revista:
J Neuroradiol
Año:
2012
Tipo del documento:
Article
País de afiliación:
Francia