Copper- and iron-catalyzed decarboxylative tri- and difluoromethylation of α,ß-unsaturated carboxylic acids with CF3SO2Na and (CF2HSO2)2Zn via a radical process.
Org Lett
; 15(2): 406-9, 2013 Jan 18.
Article
en En
| MEDLINE
| ID: mdl-23305217
A copper-catalyzed decarboxylative trifluoromethylation of various α,ß-unsaturated carboxylic acids by using a stable and inexpensive solid, sodium trifluoromethanesulfinate (CF(3)SO(2)Na, Langlois reagent), was developed. In addition, an iron-catalyzed difluoromethylation of aryl-substituted acrylic acids by using zinc difluoromethanesulfinate (DFMS, (CF(2)HSO(2))(2)Zn, Baran reagent) via a similar radical process was also achieved.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Ácidos Carboxílicos
/
Cobre
/
Alquenos
/
Hidrocarburos Fluorados
/
Hierro
Idioma:
En
Revista:
Org Lett
Asunto de la revista:
BIOQUIMICA
Año:
2013
Tipo del documento:
Article