Forearm blood flow response to acute exercise in obese and non-obese males.
Eur J Appl Physiol
; 113(8): 2015-23, 2013 Aug.
Article
en En
| MEDLINE
| ID: mdl-23558924
ABSTRACT
Chronic exercise is thought to improve endothelium-dependent vasodilation; however, few studies have evaluated the effects of acute exercise on microvascular vasodilatory capacity (MVC). Moreover, no studies have compared MVC responses in obese and non-obese individuals following acute exercise. To evaluate MVC, utilizing forearm blood flow (FBF) and excess blood flow (EBF) before and up to 48 h after a single exercise bout to elicit peak oxygen consumption (VO2 peak) in obese and non-obese males. Twelve obese (37.0 ± 1.1 kg/m(2)) and 12 non-obese (21.9 ± 0.3 kg/m(2)) males volunteered to participate. FBF measures, before and during reactive hyperemia (RH), were obtained prior to (PRE-E), immediately after (POST-E), and at 1 (POST-1), 2 (POST-2), 24 (POST-24), and 48 (POST-48) hours after exercise. EBF, was calculated as the difference between FBF, before and during RH. Blood samples were obtained to evaluate the response of interleukin-6 (IL-6) and tumor necrosis factor alpha (TNF-α), which are potential modifiers of MVC. FBF before and during RH were significantly (P < 0.05) increased in both groups POST-E. The EBF magnitude of change from PRE-E was significantly (P < 0.05) elevated in non-obese when compared with obese males. Although not related to MVC, concentrations of IL-6 significantly decreased between POST-2 and POST-24 in both groups. An acute bout of exercise designed to elicit VO2 peak significantly increased forearm MVC in non-obese and obese males, although the magnitude of change in EBF from PRE-E to POST-E was greater in non-obese males.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Ejercicio Físico
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Antebrazo
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Obesidad
Tipo de estudio:
Observational_studies
Límite:
Adult
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Humans
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Male
Idioma:
En
Revista:
Eur J Appl Physiol
Asunto de la revista:
FISIOLOGIA
Año:
2013
Tipo del documento:
Article
País de afiliación:
Estados Unidos