The tert-butyl side chain: a powerful means to lock peptoid amide bonds in the cis conformation.
Org Lett
; 15(9): 2246-9, 2013 May 03.
Article
en En
| MEDLINE
| ID: mdl-23590358
ABSTRACT
The very simple sterically hindered tert-butyl side chain exerts complete control over the peptoid amide geometry which only exists in the cis conformation. It is exemplified in NtBu glycine homo-oligomers and in linear oligopeptoids designed with an alternating cis-trans backbone amide pattern.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Oligopéptidos
/
Peptoides
/
Amidas
/
Glicina
Idioma:
En
Revista:
Org Lett
Asunto de la revista:
BIOQUIMICA
Año:
2013
Tipo del documento:
Article
País de afiliación:
Francia