Quinasa 2 de Adhesión Focal/metabolismo; Sistema de Señalización de MAP Quinasas; Macrófagos/metabolismo; Estrés Oxidativo; Proteínas Proto-Oncogénicas pp60(c-src)/metabolismo; Receptores Purinérgicos P2X7/fisiología; Animales; Calcio/metabolismo; Línea Celular; Humanos; Transporte Iónico; Macrófagos/enzimología; Ratones

2-(1-(3 dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1h-indol-3-yl)maleimide; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one; 2',3'-O-(4-benzoyl-benzoyl) ATP; 2',7'-dichlorodihydrofluorescein diacetate; 2',7'-dichlorofluorescein; 4-[5-(4-fluorophenyl)-2-[4-(methylsulfonyl)phenyl]-1H-imidazol-4-yl]pyridine; 4-amino-5-(4-chlorophenyl)-7-(dimethylethyl) pyrazolo[3,4-d]pyrimidine; 8-amino-5-chloro-7-phenylpyrido [3,4-d]pyridazine-1,4(2H,3H) dione; Bz-ATP; Calcium; DCF; DCFH(2)DA; DMSO; DPI; EGFR; ERK1/2; Epidermal Growth Factor Receptor; Fura-2 AM; Fura-2-acetoxymethylester; Gö6983; HBSS; Hanks's balanced salt solution; IL-1ß; JNK; L-012; LPS; MAPKs; Macrophage; Mitogen-activated protein kinase; N-Methyl-N-[2-[[[2-[(2,3-dihydro-2- oxo-1H-indol-5-yl)amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]methyl]phenyl]methanesulfonamide; Oxidative stress; P2X7 receptor channels; P2X7R; PD98059; PF431396; PI3K; PLD; PMA; PP2; Purinergic receptor; ROS; SB203580; SB239063; SS; TNFα; WB; Western blot; c-Jun N-terminal kinase; dimethlysulfoxide; diphenyleneiodonium; extracellular regulated kinases 1 and 2; interleukin-1ß; lipopolysaccharide; mitogen-activated protein kinases; phorbol myristate acetate; phosphatidylinositol 3 kinase; phospholipase D; reactive oxygen species; saline solution; trans-4-[4-(4-fluorophenyl)-5-(2-methoxy-4-pyrimidinyl)-1H-imidazol-1-yl]cyclohexanol; tumor necrosis factor α