Terahertz spectroscopy for the assessment of burn injuries in vivo.
J Biomed Opt
; 18(7): 077004, 2013 Jul.
Article
en En
| MEDLINE
| ID: mdl-23860943
ABSTRACT
A diagnosis criterion is proposed for noninvasive grading of burn injuries using terahertz radiation. Experimental results are presented from in vivo terahertz time-domain spectroscopy of second- and third-degree wounds, which are obtained in a 72-hour animal study. During this period, the change in the spectroscopic response of the burned tissue is studied. It is shown that terahertz waves are sensitive not only to the postburn formation of interstitial edema, but also to the density of skin structures derived from image processing analysis of histological sections. Based on these preliminary results, it is suggested that the combination of these two effects, as probed by terahertz spectroscopy of the tissue, may ultimately be used to differentiate partial-thickness burns that will naturally heal from those that will require surgical intervention.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Piel
/
Quemaduras
/
Diagnóstico por Imagen
/
Espectroscopía de Terahertz
Tipo de estudio:
Diagnostic_studies
Límite:
Animals
Idioma:
En
Revista:
J Biomed Opt
Asunto de la revista:
ENGENHARIA BIOMEDICA
/
OFTALMOLOGIA
Año:
2013
Tipo del documento:
Article
País de afiliación:
Estados Unidos