Multimodal imaging of subventricular zone neural stem/progenitor cells in the cuprizone mouse model reveals increased neurogenic potential for the olfactory bulb pathway, but no contribution to remyelination of the corpus callosum.

Guglielmetti, Caroline; Praet, Jelle; Rangarajan, Janaki Raman; Vreys, Ruth; De Vocht, Nathalie; Maes, Frederik; Verhoye, Marleen; Ponsaerts, Peter; Van der Linden, Annemie

Guglielmetti, Caroline; Praet, Jelle; Rangarajan, Janaki Raman; Vreys, Ruth; De Vocht, Nathalie; Maes, Frederik; Verhoye, Marleen; Ponsaerts, Peter; Van der Linden, Annemie.

Afiliación

Guglielmetti C; Bio-Imaging Lab, University of Antwerp, Antwerp, Belgium.
Praet J; Bio-Imaging Lab, University of Antwerp, Antwerp, Belgium; Experimental Cell Transplantation Group, Laboratory of Experimental Hematology, Vaccine and Infectious Disease Institute (Vaxinfectio), University of Antwerp, Antwerp, Belgium.
Rangarajan JR; Medical Image Computing, ESAT/PSI, Department of Electrical Engineering, & Medical Imaging Research Center, KU Leuven & UZ Leuven, Belgium; iMinds Future Health Department, KU Leuven, Belgium.
Vreys R; Bio-Imaging Lab, University of Antwerp, Antwerp, Belgium.
De Vocht N; Bio-Imaging Lab, University of Antwerp, Antwerp, Belgium; Experimental Cell Transplantation Group, Laboratory of Experimental Hematology, Vaccine and Infectious Disease Institute (Vaxinfectio), University of Antwerp, Antwerp, Belgium.
Maes F; Medical Image Computing, ESAT/PSI, Department of Electrical Engineering, & Medical Imaging Research Center, KU Leuven & UZ Leuven, Belgium; iMinds Future Health Department, KU Leuven, Belgium.
Verhoye M; Bio-Imaging Lab, University of Antwerp, Antwerp, Belgium.
Ponsaerts P; Experimental Cell Transplantation Group, Laboratory of Experimental Hematology, Vaccine and Infectious Disease Institute (Vaxinfectio), University of Antwerp, Antwerp, Belgium.
Van der Linden A; Bio-Imaging Lab, University of Antwerp, Antwerp, Belgium. Electronic address: annemie.vanderlinden@ua.ac.be.

Neuroimage ; 86: 99-110, 2014 Feb 01.

Article en En | MEDLINE | ID: mdl-23933305

Asunto(s)

Ventrículos Cerebrales/patología; Cuerpo Calloso/patología; Enfermedades Desmielinizantes/patología; Imagen de Difusión por Resonancia Magnética/métodos; Fibras Nerviosas Mielínicas/patología; Células-Madre Neurales/patología; Bulbo Olfatorio/patología; Animales; Movimiento Celular; Rastreo Celular/métodos; Cuprizona; Enfermedades Desmielinizantes/inducido químicamente; Femenino; Ratones; Ratones Endogámicos C57BL; Microscopía Fluorescente/métodos; Imagen Multimodal/métodos; Vías Nerviosas/patología; Neurogénesis

Palabras clave

AP; APC/CC1; BG; BLI; Bioluminescence imaging; CC; CNS; Cuprizone; DV; EAE; EWD; GE; GFAP; IBA1; LVv; La; MBP; MPIO; MRI; MS; Magnetic resonance imaging; Migration; NSPC; NeuN; Neural stem cell; OB; PBS; PC; PLL; RF; RMS; ROI; Remyelination; SVZ; VOI; adenomatous polyposis coli; antero-posterior; background; bioluminescence imaging; central nervous system; corpus callosum; dorso-ventral; eGFP; enhanced green fluorescent protein; error weighted difference; experimental auto-immune encephalomyelitis; fLuc; firefly luciferase; glial fibrillary acidic protein; gradient echo; ionized calcium binding adaptor molecule; lateral; lentiviral vector; mIPs; magnetic resonance imaging; micron-sized iron oxide particles; minimum intensity projections; multiple sclerosis; myelin basic protein; neural stem progenitor cell; neuronal nuclear antigen; olfactory bulb; p.i.; p75 neurotrophin receptor; p75NTR; phosphate buffered saline; poly-l-lysine; positive control; post-injection; radio-frequency; region of interest; rostral migratory stream; sCC; splenium of the corpus callosum; subventricular zone; volume of interest

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Bulbo Olfatorio / Ventrículos Cerebrales / Enfermedades Desmielinizantes / Cuerpo Calloso / Imagen de Difusión por Resonancia Magnética / Células-Madre Neurales / Fibras Nerviosas Mielínicas Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Neuroimage Asunto de la revista: DIAGNOSTICO POR IMAGEM Año: 2014 Tipo del documento: Article País de afiliación: Bélgica

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