Regulation of the structurally dynamic N-terminal domain of progesterone receptor by protein-induced folding.

Kumar, Raj; Moure, Carmen M; Khan, Shagufta H; Callaway, Celetta; Grimm, Sandra L; Goswami, Devrishi; Griffin, Patrick R; Edwards, Dean P

Kumar, Raj; Moure, Carmen M; Khan, Shagufta H; Callaway, Celetta; Grimm, Sandra L; Goswami, Devrishi; Griffin, Patrick R; Edwards, Dean P.

Afiliación

Kumar R; the Department of Basic Sciences, Commonwealth Medical College, Scranton, Pennsylvania 18509.
Moure CM; From the Departments of Molecular and Cellular Biology and.
Khan SH; the Department of Basic Sciences, Commonwealth Medical College, Scranton, Pennsylvania 18509.
Callaway C; From the Departments of Molecular and Cellular Biology and.
Grimm SL; From the Departments of Molecular and Cellular Biology and.
Goswami D; the Department of Molecular Therapeutics, The Scripps Research Institute, Jupiter, Florida 33458, and.
Griffin PR; the Department of Molecular Therapeutics, The Scripps Research Institute, Jupiter, Florida 33458, and.
Edwards DP; From the Departments of Molecular and Cellular Biology and; Pathology and Immunology, Baylor College of Medicine, Houston, Texas 77030,. Electronic address: deane@bcm.edu.

J Biol Chem ; 288(42): 30285-30299, 2013 Oct 18.

Article en En | MEDLINE | ID: mdl-23995840

Asunto(s)

Coactivador 1 de Receptor Nuclear/metabolismo; Pliegue de Proteína; Receptores de Progesterona/metabolismo; Proteína de Unión a TATA-Box/metabolismo; Activación Transcripcional/fisiología; Secuencia de Aminoácidos; Animales; Línea Celular; Humanos; Coactivador 1 de Receptor Nuclear/química; Coactivador 1 de Receptor Nuclear/genética; Mutación Puntual; Estructura Secundaria de Proteína; Estructura Terciaria de Proteína; Receptores de Progesterona/química; Receptores de Progesterona/genética; Eliminación de Secuencia; Proteína de Unión a TATA-Box/química; Proteína de Unión a TATA-Box/genética

Palabras clave

Hydrogen Deuterium Exchange Mass; Intrinsically Disordered Proteins; Mass Spectrometry (MS); N-terminal Transcription Activation domain AF1; Progesterone; Progesterone Receptor; Protein Folding; Steroid Hormone Receptor; TATA-binding Protein

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Receptores de Progesterona / Activación Transcripcional / Pliegue de Proteína / Proteína de Unión a TATA-Box / Coactivador 1 de Receptor Nuclear Límite: Animals / Humans Idioma: En Revista: J Biol Chem Año: 2013 Tipo del documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google