Six-year pilot study on nucleic acid testing for blood donations in China.
Transfus Apher Sci
; 49(2): 318-22, 2013 Oct.
Article
en En
| MEDLINE
| ID: mdl-24007868
ABSTRACT
A six-year pilot study on nucleic acid testing for HBV, HCV and HIV-1 has been undertaken on sero-negative plasmas in mini-pool and individual donation testing at Shenzhen Blood Center. Of 307,740 sero-negative blood samples, 95 of 102 HBV DNA yields were confirmed positive, 80/95 (84.2%) were classified as occult HBV infection (OBI) and 15 (15.8%) as window period cases. Amongst OBIs, 45% carried anti-HBc only, 41.3% anti-HBc and anti-HBs and 13.7% anti-HBs only. HBV DNA yield was 13239. One HCV WP and one HIV-1 infected donations were detected. High residual risk was found in current blood donations screening in China.
Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Donantes de Sangre
/
ADN Viral
/
ARN Viral
/
Virus de la Hepatitis B
/
VIH-1
/
Hepacivirus
/
Selección de Donante
Tipo de estudio:
Observational_studies
Límite:
Female
/
Humans
/
Male
País/Región como asunto:
Asia
Idioma:
En
Revista:
Transfus Apher Sci
Asunto de la revista:
HEMATOLOGIA
Año:
2013
Tipo del documento:
Article
País de afiliación:
China