c-Src-induced activation of ceramide metabolism impairs membrane microdomains and promotes malignant progression by facilitating the translocation of c-Src to focal adhesions.

Kajiwara, Kentaro; Yamada, Takayuki; Bamba, Takeshi; Fukusaki, Eiichiro; Imamoto, Fumio; Okada, Masato; Oneyama, Chitose

Kajiwara, Kentaro; Yamada, Takayuki; Bamba, Takeshi; Fukusaki, Eiichiro; Imamoto, Fumio; Okada, Masato; Oneyama, Chitose.

Afiliación

Kajiwara K; *Department of Oncogene Research, Research Institute for Microbial Diseases, Osaka University, 3-1 Yamadaoka, Suita, Osaka 565-0871, Japan.
Yamada T; Department of Biotechnology, Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan.
Bamba T; Department of Biotechnology, Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan.
Fukusaki E; Department of Biotechnology, Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan.
Imamoto F; Department of Molecular Biology, Research Institute for Microbial Diseases, Osaka University, 3-1 Yamadaoka, Suita, Osaka 565-0871, Japan.
Okada M; *Department of Oncogene Research, Research Institute for Microbial Diseases, Osaka University, 3-1 Yamadaoka, Suita, Osaka 565-0871, Japan.
Oneyama C; *Department of Oncogene Research, Research Institute for Microbial Diseases, Osaka University, 3-1 Yamadaoka, Suita, Osaka 565-0871, Japan.

Biochem J ; 458(1): 81-93, 2014 Feb 15.

Article en En | MEDLINE | ID: mdl-24266736

Asunto(s)

Transformación Celular Neoplásica; Ceramidas/metabolismo; Adhesiones Focales; Microdominios de Membrana/fisiología; Proteína Oncogénica pp60(v-src)/fisiología; Animales; Ratones; Reacción en Cadena de la Polimerasa de Transcriptasa Inversa

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Transformación Celular Neoplásica / Ceramidas / Proteína Oncogénica pp60(v-src) / Adhesiones Focales / Microdominios de Membrana Límite: Animals Idioma: En Revista: Biochem J Año: 2014 Tipo del documento: Article País de afiliación: Japón

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