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Cancer-derived mutations in KEAP1 impair NRF2 degradation but not ubiquitination.
Hast, Bridgid E; Cloer, Erica W; Goldfarb, Dennis; Li, Heng; Siesser, Priscila F; Yan, Feng; Walter, Vonn; Zheng, Ning; Hayes, D Neil; Major, Michael B.
Afiliación
  • Hast BE; Authors' Affiliations: Department of Cell Biology and Physiology; Lineberger Comprehensive Cancer Center; and Division of Medical Oncology, Department of Internal Medicine and Otolaryngology, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill School of Medicine; Department of Computer Science, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; and Department of Pharmacology, Howard Hughes Medical Institute, University of Washington, Seattle
Cancer Res ; 74(3): 808-17, 2014 Feb 01.
Article en En | MEDLINE | ID: mdl-24322982

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Péptidos y Proteínas de Señalización Intracelular / Factor 2 Relacionado con NF-E2 / Mutación / Neoplasias Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Cancer Res Año: 2014 Tipo del documento: Article

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Péptidos y Proteínas de Señalización Intracelular / Factor 2 Relacionado con NF-E2 / Mutación / Neoplasias Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Cancer Res Año: 2014 Tipo del documento: Article