Hypoxia inducible factor 2&#945;/insulin-like growth factor receptor signal loop supports the proliferation and Oct-4 maintenance of mouse germline stem cells.

Huang, Y-H; Lin, M-H; Wang, P-C; Wu, Y-C; Chiang, H-L; Wang, Y-L; Chang, J-H; Huang, Y-K; Gu, S-Y; Ho, H-N; Ling, T-Y

Hypoxia inducible factor 2α/insulin-like growth factor receptor signal loop supports the proliferation and Oct-4 maintenance of mouse germline stem cells.

Huang, Y-H; Lin, M-H; Wang, P-C; Wu, Y-C; Chiang, H-L; Wang, Y-L; Chang, J-H; Huang, Y-K; Gu, S-Y; Ho, H-N; Ling, T-Y.

Afiliación

Huang YH; Department of Biochemistry, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan Center for Reproductive Medicine and Sciences, Taipei Medical University Hospital, Tai
Lin MH; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei, Taiwan.
Wang PC; Department of Biochemistry, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Wu YC; Department of Biochemistry, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Chiang HL; Department of Biochemistry, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Wang YL; Department of Biochemistry, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Chang JH; Department of Biochemistry, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Huang YK; Department of Pharmacology, College of Medicine, National Taiwan University, No.1, Section 1, Je-Ai Rd, Taipei, Taiwan.
Gu SY; Department of Pharmacology, College of Medicine, National Taiwan University, No.1, Section 1, Je-Ai Rd, Taipei, Taiwan.
Ho HN; Graduate Institute of Clinical Genomics, College of Medicine, National Taiwan University, Taipei, Taiwan Division of Endocrinology and Infertility, Department of Obstetrics and Gynecology, College of Medicine, National Taiwan University, Taipei Medical University, Taipei, Taiwan.
Ling TY; Department of Pharmacology, College of Medicine, National Taiwan University, No.1, Section 1, Je-Ai Rd, Taipei, Taiwan tyling@ntu.edu.tw.

Mol Hum Reprod ; 20(6): 526-37, 2014 Jun.

Article en En | MEDLINE | ID: mdl-24598112

Asunto(s)

Factores de Transcripción con Motivo Hélice-Asa-Hélice Básico/genética; Retroalimentación Fisiológica; Células Germinativas/metabolismo; Factor 3 de Transcripción de Unión a Octámeros/genética; Receptor IGF Tipo 1/genética; Animales; Animales Recién Nacidos; Factores de Transcripción con Motivo Hélice-Asa-Hélice Básico/metabolismo; Hipoxia de la Célula/genética; Proliferación Celular; Células Cultivadas; Regulación del Desarrollo de la Expresión Génica; Células Germinativas/citología; Masculino; Ratones; Factor 3 de Transcripción de Unión a Octámeros/metabolismo; Fosfatidilinositol 3-Quinasas/genética; Fosfatidilinositol 3-Quinasas/metabolismo; Proteínas Proto-Oncogénicas c-kit/genética; Proteínas Proto-Oncogénicas c-kit/metabolismo; Receptor IGF Tipo 1/metabolismo; Transducción de Señal; Serina-Treonina Quinasas TOR/genética; Serina-Treonina Quinasas TOR/metabolismo; Testículo/citología; Testículo/metabolismo

Palabras clave

germline; niche growth factor; oxygen tension; self-renewal; tissue-specific stem cells

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Receptor IGF Tipo 1 / Retroalimentación Fisiológica / Factores de Transcripción con Motivo Hélice-Asa-Hélice Básico / Factor 3 de Transcripción de Unión a Octámeros / Células Germinativas Límite: Animals Idioma: En Revista: Mol Hum Reprod Asunto de la revista: BIOLOGIA MOLECULAR / MEDICINA REPRODUTIVA Año: 2014 Tipo del documento: Article

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