Tanshinone IIA attenuates bleomycin-induced pulmonary fibrosis via modulating angiotensin-converting enzyme 2/ angiotensin-(1-7) axis in rats.

Wu, Huajie; Li, Yan; Wang, Yanxia; Xu, Dunquan; Li, Congcong; Liu, Manling; Sun, Xin; Li, Zhichao

Wu, Huajie; Li, Yan; Wang, Yanxia; Xu, Dunquan; Li, Congcong; Liu, Manling; Sun, Xin; Li, Zhichao.

Afiliación

Wu H; 1. Department of Pediatrics of Xijing Hospital, Fourth Military Medical University; ; 3. Lung Injury and Repair Center, Fourth Military Medical University;
Li Y; 4. Medical Examination Center of Beijing Military General Hospital;
Wang Y; 2. Department of Pathophysiology, Fourth Military Medical University; ; 3. Lung Injury and Repair Center, Fourth Military Medical University;
Xu D; 2. Department of Pathophysiology, Fourth Military Medical University;
Li C; 5. Department of Respiratory Medicine, Tangdu Hospital, Fourth Military Medical University.
Liu M; 2. Department of Pathophysiology, Fourth Military Medical University;
Sun X; 1. Department of Pediatrics of Xijing Hospital, Fourth Military Medical University;
Li Z; 2. Department of Pathophysiology, Fourth Military Medical University; ; 3. Lung Injury and Repair Center, Fourth Military Medical University;

Int J Med Sci ; 11(6): 578-86, 2014.

Article en En | MEDLINE | ID: mdl-24782646

Asunto(s)

Abietanos/administración & dosificación; Angiotensina I/metabolismo; Fragmentos de Péptidos/metabolismo; Peptidil-Dipeptidasa A/metabolismo; Fibrosis Pulmonar/tratamiento farmacológico; Enzima Convertidora de Angiotensina 2; Animales; Bleomicina/toxicidad; Humanos; Inflamación/inducido químicamente; Inflamación/tratamiento farmacológico; Inflamación/patología; Fibrosis Pulmonar/inducido químicamente; Ratas; Factor de Crecimiento Transformador beta/metabolismo

Palabras clave

ANG-(1-7).; Pulmonary fibrosis; Tanshinone IIA; angiotensin-converting enzyme 2; transforming growth factor beta

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Fragmentos de Péptidos / Fibrosis Pulmonar / Angiotensina I / Peptidil-Dipeptidasa A / Abietanos Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Int J Med Sci Asunto de la revista: MEDICINA Año: 2014 Tipo del documento: Article

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