Involvement of interleukin-17A-induced hypercontractility of intestinal smooth muscle cells in persistent gut motor dysfunction.

Akiho, Hirotada; Tokita, Yohei; Nakamura, Kazuhiko; Satoh, Kazuko; Nishiyama, Mitsue; Tsuchiya, Naoko; Tsuchiya, Kazuaki; Ohbuchi, Katsuya; Iwakura, Yoichiro; Ihara, Eikichi; Takayanagi, Ryoichi; Yamamoto, Masahiro

Akiho, Hirotada; Tokita, Yohei; Nakamura, Kazuhiko; Satoh, Kazuko; Nishiyama, Mitsue; Tsuchiya, Naoko; Tsuchiya, Kazuaki; Ohbuchi, Katsuya; Iwakura, Yoichiro; Ihara, Eikichi; Takayanagi, Ryoichi; Yamamoto, Masahiro.

Afiliación

Akiho H; Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan; Department of Gastroenterology, Kitakyushu Municipal Medical Center, Fukuoka, Japan.
Tokita Y; Tsumura Research Laboratories, Tsumura & Co., Ibaraki, Japan.
Nakamura K; Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Satoh K; Tsumura Research Laboratories, Tsumura & Co., Ibaraki, Japan.
Nishiyama M; Tsumura Research Laboratories, Tsumura & Co., Ibaraki, Japan.
Tsuchiya N; Tsumura Research Laboratories, Tsumura & Co., Ibaraki, Japan.
Tsuchiya K; Tsumura Research Laboratories, Tsumura & Co., Ibaraki, Japan.
Ohbuchi K; Tsumura Research Laboratories, Tsumura & Co., Ibaraki, Japan.
Iwakura Y; Division of Laboratory Animal, Research Institute for Biomedical Science, Tokyo University of Science, Chiba, Japan; Core Research for Evolutional Science and Technology (CREST), JST, Saitama, Japan.
Ihara E; Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Takayanagi R; Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Yamamoto M; Tsumura Research Laboratories, Tsumura & Co., Ibaraki, Japan.

PLoS One ; 9(5): e92960, 2014.

Article en En | MEDLINE | ID: mdl-24796324

Asunto(s)

Enteritis/metabolismo; Motilidad Gastrointestinal; Interleucina-17/metabolismo; Animales; Modelos Animales de Enfermedad; Enteritis/genética; Enteritis/patología; Activación Enzimática/genética; Subunidades alfa de la Proteína de Unión al GTP Gq-G11/genética; Subunidades alfa de la Proteína de Unión al GTP Gq-G11/metabolismo; Humanos; Quinasa I-kappa B/genética; Quinasa I-kappa B/metabolismo; Interleucina-17/genética; Interleucina-1beta/genética; Interleucina-1beta/metabolismo; MAP Quinasa Quinasa 4/genética; MAP Quinasa Quinasa 4/metabolismo; Ratones; Ratones Endogámicos BALB C; Ratones Noqueados; Miosinas/genética; Miosinas/metabolismo; Proteínas RGS/genética; Proteínas RGS/metabolismo; Proteínas Quinasas p38 Activadas por Mitógenos/genética; Proteínas Quinasas p38 Activadas por Mitógenos/metabolismo

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Interleucina-17 / Enteritis / Motilidad Gastrointestinal Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2014 Tipo del documento: Article País de afiliación: Japón

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