[HIV infection and T-lymphocyte behavior: results of a study in Palermo]. / Infezioni da HIV e comportamento di linfociti T: risultati di uno studio palermitano.
Ann Ig
; 1(1-2): 45-50, 1989.
Article
en It
| MEDLINE
| ID: mdl-2483080
ABSTRACT
The acquired immunodeficiency syndrome (AIDS) is caused by the HIV infection in people with an already impaired immunological system. The seroprevalence follow-up of different markers of HIV should seem to suggest to predict the course of the disease as well as the T4/T8 ratio did. We examined 111 at risk anti-HIV positive people according to these parameters in comparison with their clinical situation. Serum samples from these subjects were examined by means of the ELISA method for anti-ENV/CORE antibodies and HIV antigen, followed by a Western Blot confirmation. The T4/T8 ratio was controlled and measured by means of monoclonal immunofluorescent antibody test. Sixty six out of eighty three (79.5%) symptomatic patients showed a less than 1.0 T4/T8 ratio in comparison with 15/28 (53.6%) asymptomatic people (p less than 0.01) while no difference was seen in the same patients according to the presence or not of anti-core antibodies. In some patients it was possible to observe a positive trend in the T4/T8 ratio.
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Bases de datos:
MEDLINE
Asunto principal:
Linfocitos T CD4-Positivos
/
Infecciones por VIH
/
Recuento de Leucocitos
Tipo de estudio:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Humans
Idioma:
It
Revista:
Ann Ig
Asunto de la revista:
MICROBIOLOGIA
/
SAUDE PUBLICA
Año:
1989
Tipo del documento:
Article