Activation of epidermal growth factor receptor mediates mucin production stimulated by p40, a Lactobacillus rhamnosus GG-derived protein.

Wang, Lihong; Cao, Hailong; Liu, Liping; Wang, Bangmao; Walker, W Allan; Acra, Sari A; Yan, Fang

Wang, Lihong; Cao, Hailong; Liu, Liping; Wang, Bangmao; Walker, W Allan; Acra, Sari A; Yan, Fang.

Afiliación

Wang L; From the Department of Pediatrics, Division of Gastroenterology, Hepatology and Nutrition, Vanderbilt University Medical Center, Nashville, Tennessee 37232.
Cao H; the Department of Gastroenterology, Tianjin Medical University General Hospital, Tianjin 300052, China, and.
Liu L; From the Department of Pediatrics, Division of Gastroenterology, Hepatology and Nutrition, Vanderbilt University Medical Center, Nashville, Tennessee 37232.
Wang B; the Department of Gastroenterology, Tianjin Medical University General Hospital, Tianjin 300052, China, and.
Walker WA; the Mucosal Immunology and Biology Research Center, Massachusetts General Hospital, Harvard University Medical School, Boston, Massachusetts 02114.
Acra SA; From the Department of Pediatrics, Division of Gastroenterology, Hepatology and Nutrition, Vanderbilt University Medical Center, Nashville, Tennessee 37232.
Yan F; From the Department of Pediatrics, Division of Gastroenterology, Hepatology and Nutrition, Vanderbilt University Medical Center, Nashville, Tennessee 37232, fang.yan@vanderbilt.edu.

J Biol Chem ; 289(29): 20234-44, 2014 Jul 18.

Article en En | MEDLINE | ID: mdl-24895124

Asunto(s)

Proteínas Bacterianas/farmacología; Receptores ErbB/metabolismo; Lacticaseibacillus rhamnosus/metabolismo; Mucinas/biosíntesis; Animales; Apoptosis; Línea Celular; Colon/citología; Colon/metabolismo; Receptores ErbB/antagonistas & inhibidores; Receptores ErbB/deficiencia; Receptores ErbB/genética; Humanos; Mucosa Intestinal/citología; Mucosa Intestinal/metabolismo; Ratones; Ratones Endogámicos C57BL; Ratones Noqueados; Mucina 2/genética; Probióticos/farmacología; ARN Interferente Pequeño/genética; Activación Transcripcional; Regulación hacia Arriba

Palabras clave

Apoptosis; Epidermal Growth Factor Receptor (EGFR); Goblet Cell; Intestine; Lactobacillus rhamnosus GG; Mucin; Mucus; Probiotic; Probiotics

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Proteínas Bacterianas / Lacticaseibacillus rhamnosus / Receptores ErbB / Mucinas Límite: Animals / Humans Idioma: En Revista: J Biol Chem Año: 2014 Tipo del documento: Article

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