Specific disruption of thalamic inputs to the auditory cortex in schizophrenia models.

Chun, Sungkun; Westmoreland, Joby J; Bayazitov, Ildar T; Eddins, Donnie; Pani, Amar K; Smeyne, Richard J; Yu, Jing; Blundon, Jay A; Zakharenko, Stanislav S

Chun, Sungkun; Westmoreland, Joby J; Bayazitov, Ildar T; Eddins, Donnie; Pani, Amar K; Smeyne, Richard J; Yu, Jing; Blundon, Jay A; Zakharenko, Stanislav S.

Afiliación

Chun S; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Westmoreland JJ; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Bayazitov IT; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Eddins D; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Pani AK; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Smeyne RJ; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Yu J; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Blundon JA; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Zakharenko SS; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA. stanislav.zakharenko@stjude.org.

Science ; 344(6188): 1178-82, 2014 Jun 06.

Article en En | MEDLINE | ID: mdl-24904170

Asunto(s)

Síndrome de Deleción 22q11/genética; Corteza Auditiva/metabolismo; Haploinsuficiencia; Proteínas de Unión al ARN/genética; Receptores de Dopamina D2/biosíntesis; Esquizofrenia/genética; Tálamo/metabolismo; Síndrome de Deleción 22q11/tratamiento farmacológico; Animales; Antipsicóticos/uso terapéutico; Modelos Animales de Enfermedad; Resistencia a Medicamentos/genética; Ratones; Ratones Mutantes; MicroARNs/metabolismo; Receptores de Dopamina D2/genética; Esquizofrenia/tratamiento farmacológico; Transmisión Sináptica/genética

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Esquizofrenia / Corteza Auditiva / Tálamo / Proteínas de Unión al ARN / Receptores de Dopamina D2 / Síndrome de Deleción 22q11 / Haploinsuficiencia Límite: Animals Idioma: En Revista: Science Año: 2014 Tipo del documento: Article País de afiliación: Estados Unidos

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