Long-term ongoing pregnancy rate and mode of conception after a positive and negative post-coital test.
Acta Obstet Gynecol Scand
; 93(9): 913-20, 2014 Sep.
Article
en En
| MEDLINE
| ID: mdl-24946691
ABSTRACT
OBJECTIVE:
Many fertility clinics have decided to abolish the post-coital test. Yet, it is a significant factor in prognostic models that predict the spontaneous pregnancy rate within one year. The aim of this study was to evaluate (1) the long-term outcome of infertile couples with a positive or a negative post-coital test during their fertility work-up and (2) the contribution of the different modes of conception.DESIGN:
Retrospective cohort study.SETTING:
Three fertility clinics in the Netherlands, of which two are secondary care training hospitals and is a one tertiary care academic training hospital. POPULATION 2476 newly referred infertile couples, where a post-coital test was performed in 1624 couples.METHODS:
After basic fertility work-up, couples were treated according to the national treatment protocols. MAIN OUTCOMEMEASURES:
Spontaneous and overall ongoing pregnancy rate.RESULTS:
The spontaneous and overall ongoing pregnancy rates after three years were 37.7 and 77.5% after a positive post-coital test compared with 26.9 and 68.8% after a negative test (p < 0.001). Even in couples with severe male factor infertility (total motile sperm count <3) (p = 0.005) and mild male factor infertility (total motile sperm count 3-20) (p < 0.001), there was a significantly higher spontaneous ongoing pregnancy rate, justifying expectant management.CONCLUSION:
After a follow-up of three years a positive post-coital test is still associated with a higher spontaneous and a higher overall ongoing pregnancy rate, even in couples with severe male factor infertility.Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Índice de Embarazo
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Fertilización
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Infertilidad
Tipo de estudio:
Guideline
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Límite:
Adolescent
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Adult
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Female
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Humans
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Male
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Middle aged
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Pregnancy
Idioma:
En
Revista:
Acta Obstet Gynecol Scand
Año:
2014
Tipo del documento:
Article
País de afiliación:
Países Bajos