Posterior reversible encephalopathy syndrome in pediatric acute leukemia: Case series and literature review.
Indian J Med Paediatr Oncol
; 35(1): 79-82, 2014 Jan.
Article
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| MEDLINE
| ID: mdl-25006290
ABSTRACT
Posterior reversible encephalopathy syndrome (PRES) is a neurotoxic state coupled with a unique radio imaging appearance. We describe this rare, mostly reversible condition in five cases undergoing similar treatment under preset protocol (MCP-841) for acute lymphoblastic leukemia (ALL) at our centre. Hypertension is a well-known adverse effect of high-dose corticosteroid therapy primarily mediated by its effects on the mineralocorticoid receptor especially in pediatric population and we hypothesize that this may be the etiology of PRES in two of these patients.
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MEDLINE
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Guideline
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Systematic_reviews
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En
Revista:
Indian J Med Paediatr Oncol
Año:
2014
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Article
País de afiliación:
India