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Isoliquiritigenin, a flavonoid from licorice, blocks M2 macrophage polarization in colitis-associated tumorigenesis through downregulating PGE2 and IL-6.
Zhao, Haixia; Zhang, Xinhua; Chen, Xuewei; Li, Ying; Ke, Zunqiong; Tang, Tian; Chai, Hongyan; Guo, Austin M; Chen, Honglei; Yang, Jing.
Afiliación
  • Zhao H; Department of Pharmacology, School of Medicine, Wuhan University, Wuhan 430071, China.
  • Zhang X; Department of Liver, Biliary And Pancreatic Tumors, Hubei Cancer Hospital, Wuhan 430079, China.
  • Chen X; Department of Pharmacology, School of Medicine, Wuhan University, Wuhan 430071, China.
  • Li Y; Department of Pharmacology, School of Medicine, Wuhan University, Wuhan 430071, China.
  • Ke Z; Department of Pharmacology, School of Medicine, Wuhan University, Wuhan 430071, China.
  • Tang T; Department of Oncology, Renmin Hospital of Wuhan University, Wuhan 430060, China.
  • Chai H; Center for Gene Diagnosis, Zhongnan Hospital, Wuhan University, Wuhan 430071, China.
  • Guo AM; Department of Pharmacology, School of Medicine, Wuhan University, Wuhan 430071, China; Department of Pharmacology, New York Medical College, Valhalla, NY 10595, United States.
  • Chen H; Department of Pathology and Pathophysiology, School of Medicine, Wuhan University, Wuhan 430071, China. Electronic address: hl-chen@whu.edu.cn.
  • Yang J; Department of Pharmacology, School of Medicine, Wuhan University, Wuhan 430071, China. Electronic address: yangjingliu2013@163.com.
Toxicol Appl Pharmacol ; 279(3): 311-321, 2014 Sep 15.
Article en En | MEDLINE | ID: mdl-25026504
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Dinoprostona / Interleucina-6 / Colitis / Neoplasias del Colon / Chalconas / Inhibidores Enzimáticos / Glycyrrhiza / Macrófagos Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals Idioma: En Revista: Toxicol Appl Pharmacol Año: 2014 Tipo del documento: Article País de afiliación: China
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Dinoprostona / Interleucina-6 / Colitis / Neoplasias del Colon / Chalconas / Inhibidores Enzimáticos / Glycyrrhiza / Macrófagos Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals Idioma: En Revista: Toxicol Appl Pharmacol Año: 2014 Tipo del documento: Article País de afiliación: China