Discontinuation of somatic medication during psychiatric hospitalization.
Ann Pharmacother
; 48(11): 1415-24, 2014 Nov.
Article
en En
| MEDLINE
| ID: mdl-25078262
ABSTRACT
BACKGROUND:
Psychiatric hospitalization can increase the risk of discontinuation of pharmacotherapy, which may negatively influence patients' health.OBJECTIVE:
To investigate the association between psychiatric hospitalization and discontinuation of somatic medication.METHODS:
A retrospective crossover study was performed in patients admitted to a psychiatric hospital (index date), who had got somatic medication dispensed during the 3 months prior to hospitalization. Discontinuation of somatic medication was investigated at the following time points index date and 3, 6, and 9 months before the index date. Relative risks (RR) with 95% confidence intervals (95% CIs) of discontinuing somatic medication at the index date versus the time points before the index date were estimated using Cox regression.RESULTS:
In all, 471 hospitalized patients were included in the study; 38.9% of the patients were discontinuers on the index date. RR for discontinuation of ≥1 somatic medication was 1.88 (95% CI=1.55-2.27) at the index date compared with the other time points and highest for patients<45 years (RR=2.83; 95% CI=1.92-4.18).CONCLUSIONS:
Psychiatric hospitalization was associated with an almost doubled risk of discontinuation of somatic medication. Future studies should address the influence of discontinuation of care on patients' health.Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Continuidad de la Atención al Paciente
/
Quimioterapia
/
Cumplimiento de la Medicación
Tipo de estudio:
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Límite:
Adult
/
Aged
/
Female
/
Humans
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Male
/
Middle aged
Idioma:
En
Revista:
Ann Pharmacother
Asunto de la revista:
FARMACOLOGIA
/
TERAPIA POR MEDICAMENTOS
Año:
2014
Tipo del documento:
Article
País de afiliación:
Países Bajos