Food hypersensitivity in adult patients with atopic dermatitis in Korea.
Clin Exp Dermatol
; 40(1): 6-10, 2015 Jan.
Article
en En
| MEDLINE
| ID: mdl-25224762
ABSTRACT
BACKGROUND:
It is known that atopic dermatitis (AD) is associated with food or environmental allergens and increased levels of serum IgE. However, the role of hypersensitivity to food antigens in adult patients remains controversial.AIM:
To evaluate the association between food hypersensitivity and AD in 126 adult Korean participants.METHODS:
Patients with AD were assessed for a previous history of food hypersensitivity that aggravated the symptoms of AD. Blood samples were taken from the patients to measure food allergen-specific IgE. Based on history and laboratory results, open oral food challenge (OFC) tests were performed.RESULTS:
Of 126 participants, 33 (26.2%) claimed to have experienced previous food hypersensitivity. Both pork and wheat (n = 5 each) were the main foods mentioned, followed by beef (n = 4) and shellfish (n = 3). We found that 20 participants (15.9%) had raised levels of food-specific IgE, with beef (n = 7), pork (n = 6), milk (n = 5) and wheat (n = 5) being the most common (some patients had more than one). However, when the open OFC tests were conducted in 48 participants with self-reported food hypersensitivity or raised levels of food-specific IgE, only one showed a positive reaction; this participant had a previous history of pork consumption exacerbating AD.CONCLUSIONS:
Although some participants claimed to have a history of AD aggravation related to food intake, when an open OFC test was conducted, few of them had positive results. Our study result indicates that there is a positive reaction rate of only 0.79% for adults. We therefore conclude that adults are less sensitive than children with regard to the association between AD and food hypersensitivity.
Texto completo:
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Bases de datos:
MEDLINE
Asunto principal:
Dermatitis Atópica
/
Hipersensibilidad a los Alimentos
Límite:
Adolescent
/
Adult
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Female
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Humans
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Male
/
Middle aged
País/Región como asunto:
Asia
Idioma:
En
Revista:
Clin Exp Dermatol
Año:
2015
Tipo del documento:
Article